Metoprolol is a beta-blocker that improves blood flow and circulation by relaxing blood vessels and slowing the heart rate. It is used to treat chest pain, heart failure, hypertension, myocardial infarction, and atrial fibrillation. Show
Generic names: Metoprolol succinate (extended-release), metoprolol tartrate Brand names: Toprol, Toprol-XL (extended-release), Lopressor Pharmacologic class: Beta-adrenergic blocker Therapeutic class: Antihypertensive, antianginal Mechanism of action: Metoprolol blocks beta1-receptors (heart) without effect on beta2-receptors (lungs, uterus, smooth muscle). Metoprolol decreases cardiac output and reduces heart rate. Indications for use: Hypertension, angina, heart failure. Off-label uses include ventricular arrhythmias, tachycardia, tremors, and anxiety. Precautions and contraindications: Do not use with bradycardia, second or third-degree heart blocks, or systolic blood pressure below 100 mm Hg. Take caution in patients with renal or liver impairment. Not for use in children. Drug Interactions
Adverse Effects
Administration ConsiderationsAvailable preparations: IV (tartrate), tablets, extended-release tablets (succinate) Dosages for adults: Dosage is dependent on use. For hypertension: 50 to 100 mg PO daily or BID. For angina, 100 mg PO daily or BID. For MI, three bolus injections of 5 mg are given 2 minutes apart. If tolerated, a PO dose of 50 mg is given 15 minutes later and then continued every 6 hours for 48 hours, and then 100 mg BID thereafter. For symptomatic heart failure, 25 mg PO daily. Dosages for children: Safety has not been established. Route Onset Peak Duration PO tablets 15 minutes 1 hour 6-12 hours PO extended 15 minutes 6-12 hours 24 hours IV Immediate 20 minutes 5-8 hoursNursing Considerations for MetoprololRelated Nursing Diagnoses
Nursing Assessment
Nursing Interventions
Patient Teaching Associated with Metoprolol
This is not an all-inclusive list of possible drug interactions, adverse effects, precautions, nursing considerations, or patient instructions. Please consult further with a pharmacist for complete information. What the nurse should instruct when teaching the patient with angina about taking nitroglycerin tablets?Adults—1 tablet placed under the tongue or between the cheek and gum at the first sign of an angina attack. 1 tablet may be used every 5 minutes as needed, for up to 15 minutes. Do not take more than 3 tablets in 15 minutes.
What instruction should the nurse provide to the patient who needs to apply nitroglycerin ointment?Do not rub or massage the ointment into the skin. Spread it in a thin, even layer, and cover an area of skin that is the same size each time it is applied. Apply the ointment to skin with little or no hair that is free of scars, cuts, or irritation.
Which intervention is recommended for a patient with angina?Angioplasty with stenting.
Angioplasty with stenting may be a good treatment option for those with unstable angina or if lifestyle changes and medications don't effectively treat chronic, stable angina.
What is the purpose of antianginal medication therapy?The goals of drug therapy for angina are to relieve ischemia, reduce the frequency and severity of angina attacks, and prevent heart attack. Medications that control angina symptoms and ischemia include nitrates, beta-blockers, and calcium channel blockers.
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