One answer from each of the following questions is correct. To find out whether you are right or wrong just click on the answer. To go back and read a question's topic in full click the arrow after each question to take you to the relevant page. Show 1. Which of the following is not involved in first line defence? 2. Natural killers cells are found in all of the following except: 3. Wandering macrophages are phagocytes that develop from: 4. Which is not one of the four characteristic symptoms of inflammation? 5. Which of the following is not involved in specific immunity? 6. Which of the following immunoglobulins is responsible for most allergic and hypersensitivity reactions? 7. Chemicals released from mast cells during an allergic reaction include all of the following except: The immune response is how your body recognizes and defends itself against bacteria, viruses, and substances that appear foreign and harmful. InformationThe immune system protects the body from possibly harmful substances by recognizing and responding to antigens. Antigens are substances (usually proteins) on the surface of cells, viruses, fungi, or bacteria. Nonliving substances such as toxins, chemicals, drugs, and foreign particles (such as a splinter) can also be antigens. The immune system recognizes and destroys, or tries to destroy, substances that contain antigens. Your body's cells have proteins that are antigens. These include a group of antigens called HLA antigens. Your immune system learns to see these antigens as normal and usually does not react against them. INNATE IMMUNITY Innate, or nonspecific, immunity is the defense system with which you were born. It protects you against all antigens. Innate immunity involves barriers that keep harmful materials from entering your body. These barriers form the first line of defense in the immune response. Examples of innate immunity include:
Innate immunity also comes in a protein chemical form, called innate humoral immunity. Examples include the body's complement system and substances called interferon and interleukin-1 (which causes fever). If an antigen gets past these barriers, it is attacked and destroyed by other parts of the immune system. ACQUIRED IMMUNITY Acquired immunity is immunity that develops with exposure to various antigens. Your immune system builds a defense against that specific antigen. PASSIVE IMMUNITY Passive immunity is due to antibodies that are produced in a body other than your own. Infants have passive immunity because they are born with antibodies that are transferred through the placenta from their mother. These antibodies disappear between ages 6 and 12 months. Passive immunization may also be due to injection of antiserum, which contains antibodies that are formed by another person or animal. It provides immediate protection against an antigen, but does not provide long-lasting protection. Immune serum globulin (given for hepatitis exposure) and tetanus antitoxin are examples of passive immunization. BLOOD COMPONENTS The immune system includes certain types of white blood cells. It also includes chemicals and proteins in the blood, such as antibodies, complement proteins, and interferon. Some of these directly attack foreign substances in the body, and others work together to help the immune system cells. Lymphocytes are a type of white blood cell. There are B and T type lymphocytes.
As lymphocytes develop, they normally learn to tell the difference between your own body tissues and substances that are not normally found in your body. Once B cells and T cells are formed, a few of those cells will multiply and provide "memory" for your immune system. This allows your immune system to respond faster and more efficiently the next time you are exposed to the same antigen. In many cases, it will prevent you from getting sick. For example, a person who has had chickenpox or has been immunized against chickenpox is immune from getting chickenpox again.  INFLAMMATION The inflammatory response (inflammation) occurs when tissues are injured by bacteria, trauma, toxins, heat, or any other cause. The damaged cells release chemicals including histamine, bradykinin, and prostaglandins. These chemicals cause blood vessels to leak fluid into the tissues, causing swelling. This helps isolate the foreign substance from further contact with body tissues. The chemicals also attract white blood cells called phagocytes that "eat" germs and dead or damaged cells. This process is called phagocytosis. Phagocytes eventually die. Pus is formed from a collection of dead tissue, dead bacteria, and live and dead phagocytes. IMMUNE SYSTEM DISORDERS AND ALLERGIES Immune system disorders occur when the immune response is directed against body tissue, is excessive, or is lacking. Allergies involve an immune response to a substance that most people's bodies perceive as harmless. IMMUNIZATION Vaccination (immunization) is a way to trigger the immune response. Small doses of an antigen, such as dead or weakened live viruses, are given to activate immune system "memory" (activated B cells and sensitized T cells). Memory allows your body to react quickly and efficiently to future exposures. COMPLICATIONS DUE TO AN ALTERED IMMUNE RESPONSE An efficient immune response protects against many diseases and disorders. An inefficient immune response allows diseases to develop. Too much, too little, or the wrong immune response causes immune system disorders. An overactive immune response can lead to the development of autoimmune diseases, in which antibodies form against the body's own tissues. Complications from altered immune responses include:
Alternative NamesInnate immunity; Humoral immunity; Cellular immunity; Immunity; Inflammatory response; Acquired (adaptive) immunity Patient Instructions
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ReferencesAbbas AK, Lichtman AH, Pillai S. Properties and overview of immune responses. In: Abbas AK, Lichtman AH, Pillai S, eds. Cellular and Molecular Immunology. 10th ed. Philadelphia, PA: Elsevier; 2022:chap 1. Bankova L, Barrett N. Innate immunity. In: Burks AW, Holgate ST, O'Hehir RE, et al, eds. Middleton's Allergy: Principles and Practice. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 1. Firestein GS, Stanford SM. Mechanisms of inflammation and tissue repair. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 42. Tuano KS, Chinen J. Adaptive immunity. In: Burks AW, Holgate ST, O'Hehir RE, et al, eds. Middleton's Allergy: Principles and Practice. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 2. Review Date 1/23/2022Updated by: Stuart I. Henochowicz, MD, FACP, Clinical Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, Georgetown University Medical School, Washington, DC. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. What is involved in specific immunity?Specific immunity is acquired during the organism's lifetime and involves the activation of white blood cells (B and T lymphocytes), which distinguish and react to foreign substances.
Which of the following cell is not involved in specific immunity?Phagocytes are the component of non-specific immune response and kill the pathogens that invade the body.
Which of the following is involved in specific immunity quizlet?Specific immunity involves antibodies, T cells, and B cells.
Which of the following is an example of specific immunity?A specific immunity example is the DTaP vaccine. It vaccinates against Diphtheria, Tetanus, and Pertussis, and contains inactivated forms of toxins, produced by the pathogens that cause these diseases.
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